The primary aim is to facilitate an overall well-being for patients suffering from incurable neurological disorders through Neuroregenerative Rehabilitative Therapy (NRRT). In addition to the above, providing support to cellular therapy research & regenerative medicine and increasing awareness about its applications are supplementary objectives.
In the past donated organs were transplanted to replace the diseased or failed organs in the recipients. Soon the number of recipients exceeded the number of donated. To overcome this demand, cell therapy offered the possibility of replacement of the damaged cells of tissue with new cells. Stem cell infusion helps to treat a plethora of conditions including cerebral palsy, spinal cord injury, intellectual disability, and other neurodegenerative syndromes as well.
Stem cells have the potential to develop into different cells of the tissues (of the body) and the ability of self-renewal. When serving as a repair system, the stem cells divide without limit as long as the person is alive. As they divide, they remain as stem cells or develop into cells with more specialized functions, like a brain cell or a muscle cell.
Stem cells, from different sources, have three common properties: The stem cells do not have tissue-specific structures to perform specialized functions.
Impairments linked to neuromuscular conditions are usually irreversible due to inadequate cell regeneration or impaired cells in the central nervous system. It was observed that the cellular characteristics of autologous stem cells had the capability of treating major neurological disorders without incurring any side effects. With their neurotrophic properties, self-renewal & differentiation capacity, and immune modulation effects, the bone marrow-derived stem cells are considered as a promising candidate for treating disorders related to the nervous system.
For cell treatment, bone marrow derived mesenchymal stem cells are isolated from the marrow tissue (extracted from the patient’s hip bone) in an expedited, painless and safe way. By centrifugation procedure, a sufficient number of stem cells are separated from the unwanted tissue within a few hours. These injectable stem cells are infused intrathecally into the spinal area or the damaged muscle points, as per the need of the patients.
These bone marrow-derived stem cells have many useful properties that lead to great clinical improvement in post-cell-based therapy. According to various clinical trials, treatment with bone marrow derived mesenchymal stem cells have shown improvement in patients with traumatic brain injury, spinal cord injury and other neurological disorders through axonal sprouting and remyelination, potential to replace/protect the damaged neurons/cells, and neovascularization.
How do the infused stem cells act? Once infused into the body,
– The infused stem cells journey toward the nervous system and blend into the neural circuits to mend or improve the disrupted synaptic transmission.
– Post infusion, improved neuropathological condition, upregulated Aß clearance and reduced deposition is detected within a short period.
– The infused stem cells reduce neuroinflammation and provide protective immunomodulatory effect.
– The stem cells secrete neurotrophic influence and nerve growth factors, bringing cognitive and memory improvement in patients.
Apart from encouraging effects, renewed brain plasticity is also observed in patients following intrathecal delivery of stem cells. With the new medical breakthrough in stem cell therapy, the treatment has become a highly sought-after curative. To know about the treatment efficacy, one must understand the efficiency of stem cells in terms of engraftment, migration, cytokines and growth factors. However, cell-based therapy is a promising contribution to regenerative medicine and has gained considerable clinical attention. Read extra info on https://www.neurogenbsi.com.
Occupational therapists evaluate a child’s needs by testing his or her fine motor skills, perception and oral motor skills. By observing how the child responds to touch and movements, the therapist can determine a treatment plan. The treatment plan typically involves positioning, reaching, grasping and releasing. These skills are important for a child to develop the ability to be independent. Occupational therapy for children usually involves a form of play to keep them motivated. Many children with cerebral palsy have sensory impairments that make movement difficult. Our senses help us recognize changes in temperature, feel pain and to be aware of the space around us. Senses, such as touch and balance, are important for motor skills like picking up objects and walking.
A few advices to help your child with autism: Stick to a schedule. Children with ASD tend to do best when they have a highly-structured schedule or routine. Again, this goes back to the consistency they both need and crave. Set up a schedule for your child, with regular times for meals, therapy, school, and bedtime. Try to keep disruptions to this routine to a minimum. If there is an unavoidable schedule change, prepare your child for it in advance. Reward good behavior. Positive reinforcement can go a long way with children with ASD, so make an effort to “catch them doing something good.” Praise them when they act appropriately or learn a new skill, being very specific about what behavior they’re being praised for. Also look for other ways to reward them for good behavior, such as giving them a sticker or letting them play with a favorite toy.
Try to “decode” your child’s messages and communicate with him in an intelligible way. Without prejudice, learn that the things that are simple to you, come step by step for people with autism. If you enter their world, they will feel unconditional love, they will feel safe and will flourish more easily. Do things for yourself, your family and your world! Learn to look at autism as a developing thing, not as an intended thing. This vision can provide you with strategies to deal with the challenges. The challenges that a child with autism can face can give you a strong impetus to support the whole family, the future of the child and the whole environment.
US researchers are now trying to find a way to use stem cells for patients with paralysis or brain injury, for patients with type 1 diabetes, those with spinal cord injury, heart disease, people who have a heart attack or disorder neurological disorders such as multiple sclerosis. Many of the studies have been carried out on animals, and the results are in an early stage. It is important to note that the treatment with stem cells is not done with the patient’s own stem cells, because this is how the premises of the disease return are created. However, there were exceptions, proof stands a case from 2007, published in the journal Pediatric, of a child who was ill with leukemia and who was transplanted his own stem cells harvested at birth, following that 5 years after the intervention, the child to be completely healthy. Instead, it is indicated that the stem cell donors are the patient’s brother or sister. But in only 25% of cases it is shown that the brother is compatible with the patient, and 7 out of 10 patients must seek a donor outside the family.
Dr Alok Sharma is a renowned and respected Neurosurgeon, Neuroscientist and Professor across the world in medicine with an extensive surgical expertise & experience in the areas of Neurosurgery, Neuroscience and Stem cells. In 1995, Dr Alok Sharma held a place at the Karolinska hospital in Stockholm Sweden where neural transplantation was done for the first time ever in the world. In 1998, Dr Alok Sharma was placed at the University of Colorado health sciences center in Denver, USA where the world’s first randomized trial for cell transplantation was done for Parkinson’s disease. Dr Alok Sharma obtained his MBBS, M.S. and M.Ch. from the Seth G.S. Medical College & KEM Hospital of Mumbai University. Subsequently, Dr Alok Sharma did fellowships in two departments that were first to do neural transplantation. Read more info Dr Alok Sharma.